Establishment of a longitudinal growth chart corresponding to pubertal timing
نویسندگان
چکیده
منابع مشابه
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
The pubertal height growth spurt is a distinctive feature of childhood growth reflecting both the central onset of puberty and local growth factors. Although little is known about the underlying genetics, growth variability during puberty correlates with adult risks for hormone-dependent cancer and adverse cardiometabolic health. The only gene so far associated with pubertal height growth, LIN2...
متن کامل[Pubertal growth of 1,453 healthy children according to age at pubertal growth spurt onset. The Barcelona longitudinal growth study].
INTRODUCTION Pubertal growth pattern differs according to age at pubertal growth spurt onset which occurs over a five years period (girls: 8-13 years, boys: 10-15 years). The need for more than one pubertal reference pattern has been proposed. We aimed to obtain five 1-year-age-interval pubertal patterns. SUBJECTS AND METHODS Longitudinal (6 years of age-adult height) growth study of 1,453 he...
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The decline in age of pubertal timing has serious public health implications ranging from psychosocial adjustment problems to a possible increase in reproductive cancers. One biologically plausible explanation for the decline is a decrease in exposures to infections. To systematically review studies that assess the role of infection in pubertal timing, Medline, Web of Science and EMBASE were sy...
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Age at menarche varies widely between girls, is estimated to be highly heritable and is associated with long-term health outcomes, such as obesity and type 2 diabetes. Earlier pubertal maturation in boys and girls links rapid postnatal growth weight gain to later life metabolic and cardiovascular disease [1,2]. Genome-wide association studies (GWAS), which genotype hundreds of thousands of comm...
متن کاملRegulation and disorders of pubertal timing.
Disorders of pubertal timing are common and challenging problems for pediatric endocrinologists. Early or late puberty can have immediate effects on a child's psychosocial well-being and may have long-term effects on adult stature. Much is known about the regulation of the hypothalamic-pituitary-gonadal axis, but the triggers of pubertal onset in the general population remain elusive. This arti...
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ژورنال
عنوان ژورنال: Clinical Pediatric Endocrinology
سال: 2018
ISSN: 0918-5739,1347-7358
DOI: 10.1297/cpe.27.215